Bone Marrow Mononuclear Cells, Frozen

Mononuclear cells (MNCs) are composed of lymphocytes (T cells, B cells and NK cells), monocytes, dendritic cells and stem/progenitor cells. These cells are critical components of the immune system and play key roles in the humoral and cell-mediated immune responses. Mononuclear cells are commonly used in research and clinical applications in the areas of immunology, infectious disease, hematological malignancies, vaccine development, transplant therapy, and high-throughput screening.

Since our founding in 2010, CGT Global has pursued our mission to transform healthcare as we accelerate cell and gene therapy research and clinical trials, streamline the commercialization of new treatments, and map the last mile to patient access to these life-changing remedies.  By innovating each stage in the cycle; development, commercialization, and delivery, we reduce the overall cost of the care and multiply access points so that millions can receive cutting edge, life-saving gene and cell therapies.

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Description

Bone marrow MNCs are separated from whole bone marrow by red blood cell sedimentation followed by immunomagnetic depletion of non-MNCs. The highly pure population of MNCs is ideal for further isolations of specific cell types within the mononuclear fraction.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.

Additional information

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Anticoagulant

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Grade

Species

Cell and Tissue Source

Disease State

Donor Attributes

Protocols

Thawing Protocol